answer 1:5 - Further hypotheses
Positive cooperativity causes the ligand binding isotherm to be steeper than in the case of a non-cooperative monomeric protein and tyhe Hill coefficient to be higher than unity. Thus this hypothesis causes the calculated ligand binding isotherm to be even more discordant from the experimentally determined one, as shown in the figure below.
Positive cooperativity is not the correct answer! go back one step and try a different answer!